Treatment options for neuropathic pain have limited efficacy and use is fraught with dose-limiting adverse effects. The endocannabinoid system has been elucidated over the last several years, demonstrating a significant interface with pain homeostasis. Exogenous cannabinoids have been demonstrated to be effective in a range of experimental neuropathic pain models, and there is mounting evidence for therapeutic use in human neuropathic pain conditions. This article reviews the history, pharmacologic development, clinical trials results, and the future potential of nonsmoked, orally bioavailable, nonpsychoactive cannabinoids in the management of neuropathic pain
http://www.ncbi.nlm.nih.gov/pubmed/25160710?dopt=Abstract
http://www.ncbi.nlm.nih.gov/pubmed/19789075
http://www.ncbi.nlm.nih.gov/pubmed/25160710?dopt=Abstract
http://www.ncbi.nlm.nih.gov/pubmed/19789075
Comments
Post a Comment
Thanks for visiting
Peace Love Cannabis